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Antimicrobial and Antioxidant effect of Ficaria verna Huds.

Year 2021, Volume: 31 Issue: 2, 277 - 281, 30.06.2021
https://doi.org/10.29133/yyutbd.823401

Abstract

Ficaria verna Huds. is a plant belonging to the Ranunculaceae family, known as mole grass and celandine among the people. It is known to have anti-inflammatory and anti-haemorrhagic pharmaceutical effects. In this study, it was aimed to determine the antimicrobial effect of different concentrations of F. verna extracts obtained from methanol, ethanol and chloroform and the antioxidant activity of different concentrations of the extract obtained from methanol. In the results obtained, the best antimicrobial effect (17-20 mm) against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus megaterium, Salmonella thypii and Candida albicans was determined in the methanol extract of F. verna at a concentration of 1000 µg. It was observed that the scavenging effect of the DPPH radical of F. verna increased depending on increasing concentrations.

References

  • Bârlă, G. F., Poroch - Serıţan, M., Sănduleac (Tudosı), E., & Cıorneı (Ştefăroı), S. E. (2014). Antıoxıdant Actıvıty And Total Phenolıc Content In Allıum Ursınum And Ranunculus fıcarıa, Journal Of Faculty Of Food Engineering, XIII(4), 349 – 353.
  • Bhatti, M. Z., Ali, A., Saeed, A., Saeed, A., & Malik, S. A. (2015). Antimicrobial, antitumor and brine shrimp lethality assay of Ranunculus arvensis L. Extracts. Pakistan Journal of Pharmaceutical Science, 28(3), 945-949.
  • Darshan, S., Doreswamy, R., 2004. Patented antiinflammatory plant drug development from traditional medicine. Phytotherapy Research, 18, 343–357.
  • Dewick, P.M., 2009. Medicinal Natural Products: a Biosynthetic Approach. third ed. Wiley & Sons, Chichester, UK.
  • Dimitrova, D. Z, Nedialkov P., & Kitanov, G. (2010). Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria. Pharmacognosy Magazine. 6, 74-78. doi: 10.4103/0973-1296.62889
  • Doğan, Ö., Avcı, A. (2018). Bitkilerle tedavi ve ilaç etkileşimleri. Turkiye Klinik Journal Public Health, 4(1), 49-54.
  • Đurđević, L., Gajić, G., Jarić, S., Kostić, O., Mitrović, M., & Pavlović, P. (2013). Analysis of benzoic and cinnamic acid derivatives of some medicinal plants in Serbia. Archives of Biological Sciences, 65(2), 603-609. doi:10.2298/ABS1302603D
  • Erecevit Sönmez, P., Kırbağ, S., & İnci, Ş. (2019). Antifungal and Antibacterial Effect of Dodder (Cuscuta campestris) Used for Hepatitis Treatment of Mothers and Newborn Infants in Province Mardin in Turkey. Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi, 29(4), 722-730. doi: 10.29133/yyutbd.605970
  • Kaya, G. İ., Somer, N. Ü., Konyalıoğlu, S., Yalçın, H. T., Karabay Yavaşoğlu, N. Ü., Sarıkaya, B., & Önür, M. A. (2010). Antioxidant and antibacterial activities of Ranunculus marginatus var. trachycarpus and R. sprunerianus. Turkish Jorurnal of Biology, 34, 139-146. doi:10.3906/biy-0809-13
  • Malik, J., Tauchen, J., Landa , P., Kutil , Z., Marsik, P., Kloucek, P., Havlik , J., & Kokosk, L.(2017). In vitro antiinflammatory and antioxidant potential of root extracts from Ranunculaceae species. South African Journal of Botany, 109, 128–137. doi:10.1016/j.sajb.2016.12.008
  • Neag, T., Toma, C. C., Olah, N., & Ardelean, A. (2017). Polyphenols Profıle And Antıoxıdant Actıvıty Of Some Romanıan Ranunculus Specıes. Studıa Ubb Chemıa, LXII(3), 75-88. doi:10.24193/subbchem.2017.3.06
  • Ozaslan, M., & Oguzkan, S. B. (2018). Use of Plant Extracts in Alternative Medicine. Pakistan Journal of Biological Science, 21(1), 1-7. doi: 10.3923/pjbs.2018.1.7
  • Serag, M. S., Khedr, A. E. H. A., El-Amier, Y. A., & El-Afify, S. M. (2020). Bioactive constituents and allelopathic activities of the invasive weed Ranunculus sceleratus L. Nile Delta, Egypt. Journal of Experimental Sciences, 11, 1-4. doi: 10.25081/jes.2020.v11.6035
  • Sharma O. P., & Bhat T. K. (2009). DPPH antioxidant assay revisited. Food Chemistry. 113, 1202–1205. doi:10.1016/j.foodchem.2008.08.008Get

Ficaria verna Huds.’nin Antimikrobiyal ve Antioksidan Etkisi

Year 2021, Volume: 31 Issue: 2, 277 - 281, 30.06.2021
https://doi.org/10.29133/yyutbd.823401

Abstract

Ficaria verna Huds. halk arasında köstebek otu ve kırlangıç otu adıyla bilinen ve Ranunculaceae familyasına ait bir bitkidir. Antienflamatuar ve antihemorajik gibi farmasötik etkilerinin olduğu bilinmektedir. Halk arasında hemoroide karşı kullanılmaktadır. Bu çalışmada F. verna’nın metanol, etanol ve kloroformdan elde edilen ekstraklarının farklı konsantrasyonlarının antimikrobiyal etkisi ile metanoldan elde edilen ekstresinin farklı konsantrasyonlarının antioksidan aktivitesinin belirlenmesi amaçlanmıştır. Elde edilen sonuçlarda F. verna’nın metanol ekstresi 1000 µg konsantrasonda Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus megaterium, Salmonella thypii ve Candida albicans’a karşı en iyi antimikrobiyal etki (17-20mm) göstermiştir. F. verna’nın DPPH radikalinin süpürücü etkisinin artan konsantrasyonlara bağlı arttığı gözlemlenmiştir.

References

  • Bârlă, G. F., Poroch - Serıţan, M., Sănduleac (Tudosı), E., & Cıorneı (Ştefăroı), S. E. (2014). Antıoxıdant Actıvıty And Total Phenolıc Content In Allıum Ursınum And Ranunculus fıcarıa, Journal Of Faculty Of Food Engineering, XIII(4), 349 – 353.
  • Bhatti, M. Z., Ali, A., Saeed, A., Saeed, A., & Malik, S. A. (2015). Antimicrobial, antitumor and brine shrimp lethality assay of Ranunculus arvensis L. Extracts. Pakistan Journal of Pharmaceutical Science, 28(3), 945-949.
  • Darshan, S., Doreswamy, R., 2004. Patented antiinflammatory plant drug development from traditional medicine. Phytotherapy Research, 18, 343–357.
  • Dewick, P.M., 2009. Medicinal Natural Products: a Biosynthetic Approach. third ed. Wiley & Sons, Chichester, UK.
  • Dimitrova, D. Z, Nedialkov P., & Kitanov, G. (2010). Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria. Pharmacognosy Magazine. 6, 74-78. doi: 10.4103/0973-1296.62889
  • Doğan, Ö., Avcı, A. (2018). Bitkilerle tedavi ve ilaç etkileşimleri. Turkiye Klinik Journal Public Health, 4(1), 49-54.
  • Đurđević, L., Gajić, G., Jarić, S., Kostić, O., Mitrović, M., & Pavlović, P. (2013). Analysis of benzoic and cinnamic acid derivatives of some medicinal plants in Serbia. Archives of Biological Sciences, 65(2), 603-609. doi:10.2298/ABS1302603D
  • Erecevit Sönmez, P., Kırbağ, S., & İnci, Ş. (2019). Antifungal and Antibacterial Effect of Dodder (Cuscuta campestris) Used for Hepatitis Treatment of Mothers and Newborn Infants in Province Mardin in Turkey. Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi, 29(4), 722-730. doi: 10.29133/yyutbd.605970
  • Kaya, G. İ., Somer, N. Ü., Konyalıoğlu, S., Yalçın, H. T., Karabay Yavaşoğlu, N. Ü., Sarıkaya, B., & Önür, M. A. (2010). Antioxidant and antibacterial activities of Ranunculus marginatus var. trachycarpus and R. sprunerianus. Turkish Jorurnal of Biology, 34, 139-146. doi:10.3906/biy-0809-13
  • Malik, J., Tauchen, J., Landa , P., Kutil , Z., Marsik, P., Kloucek, P., Havlik , J., & Kokosk, L.(2017). In vitro antiinflammatory and antioxidant potential of root extracts from Ranunculaceae species. South African Journal of Botany, 109, 128–137. doi:10.1016/j.sajb.2016.12.008
  • Neag, T., Toma, C. C., Olah, N., & Ardelean, A. (2017). Polyphenols Profıle And Antıoxıdant Actıvıty Of Some Romanıan Ranunculus Specıes. Studıa Ubb Chemıa, LXII(3), 75-88. doi:10.24193/subbchem.2017.3.06
  • Ozaslan, M., & Oguzkan, S. B. (2018). Use of Plant Extracts in Alternative Medicine. Pakistan Journal of Biological Science, 21(1), 1-7. doi: 10.3923/pjbs.2018.1.7
  • Serag, M. S., Khedr, A. E. H. A., El-Amier, Y. A., & El-Afify, S. M. (2020). Bioactive constituents and allelopathic activities of the invasive weed Ranunculus sceleratus L. Nile Delta, Egypt. Journal of Experimental Sciences, 11, 1-4. doi: 10.25081/jes.2020.v11.6035
  • Sharma O. P., & Bhat T. K. (2009). DPPH antioxidant assay revisited. Food Chemistry. 113, 1202–1205. doi:10.1016/j.foodchem.2008.08.008Get
There are 14 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Şule İnci 0000-0002-4022-5269

Ayşe Eren This is me 0000-0002-5601-6808

Sevda Kırbağ This is me 0000-0002-4337-8236

Ahmet İsmail Özkan 0000-0002-4511-2386

Publication Date June 30, 2021
Acceptance Date May 23, 2021
Published in Issue Year 2021 Volume: 31 Issue: 2

Cite

APA İnci, Ş., Eren, A., Kırbağ, S., Özkan, A. İ. (2021). Antimicrobial and Antioxidant effect of Ficaria verna Huds. Yuzuncu Yıl University Journal of Agricultural Sciences, 31(2), 277-281. https://doi.org/10.29133/yyutbd.823401
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Yuzuncu Yil University Journal of Agricultural Sciences by Van Yuzuncu Yil University Faculty of Agriculture is licensed under a Creative Commons Attribution 4.0 International License.